About
About Caulobase
Caulobase gathers what someone new to Caulobacter crescentus needs in one place: the history, the key papers, where the data lives, and working maps of the regulatory circuit and the pathways it drives. It is also a tribute to Lucy Shapiro and Harley McAdams.
How it was checked
Every reference on the site, 299 in all, was looked up in PubMed or Crossref, and its title, journal, year and authors were copied from that record. Paper notes, network edges and pathway steps were written against the abstracts, and a claim that could not be supported from a source was left out. The last full check was on 2026-10-04. Every dataset accession was opened and matched to its paper; a resource that has gone offline is labelled as offline rather than removed.
What the diagrams are, and what they are not
The network and pathway diagrams are curated maps. They say who acts on whom, with what kind of interaction, and where the evidence is. They are not quantitative models. The phase views and the regulator traces on the home page are schematic: they show order and timing as the literature describes them, not measured concentrations. For dynamic models of the cycle, see the modelling papers in the bibliography (topic "Systems & modelling").
Names
Gene names are set in italic (ctrA) and protein names in roman (CtrA), as in the literature. NA1000 locus tags (CCNA_) and CB15 locus tags (CC_) are given where they were confirmed in UniProt.
Reuse the data
The curated data behind every page is published as plain files: 90 papers, 61 datasets and resources, 66 network interactions and 7 pathway modules. See /data/. Please cite the original papers, which are linked from every entry.
Independence
Caulobase is an independent resource. It is not affiliated with or endorsed by Stanford University, the Shapiro or McAdams laboratories, or any of the databases it links to.